Francesco Carbone Tomacelli (died 18 June 1405) was an Italian cardinal at the time of the Great Western Schism.
He supported Pope Urban VI against the claims of Antipope Clement VII after the election of the latter in 1378.
He was elected bishop of Monopoli at the end of 1382 and in the consistory of 17 December 1384 he was created cardinal.
Legate in the Kingdom of Naples to secure its support for the Roman Obedience.
Shortly before his death Innocent VII named him Cardinal-Bishop of Sabina (12 June 1405).