Francis Barrington (died 1660) was an officer in the New Model Army who led a regiment involved in the military administration of Jamaica following the English invasion of Jamaica.
He gained a commission lieutenant colonel in the expeditionary forces led by Robert Venables sent to the West Indies to seize the Spanish colonies as part of the Western Design.
He was second in command of Anthony Buller's regiment at the Siege of Santo Domingo, 1655.
[4] In order to implement the Western Design, the soldiers were put to work developing plantations under the command of their regimental officers.
Under his command the regiment started to develop Guanaboa Vale which soon became one of the most prolific plantations on the island.