Francis Anani Kofi Lodonu (born 19 November 1937) is a Ghanaian Roman Catholic Bishop.
He gained second cycle education at the prestigious Bishop Herman College at Kpando in the Volta Region from 1954 to 1957.
After his ordination to the Priesthood, Lodonu was appointed Assistant Parish Priest at Ho Sacred Heart Church.
Lodonu was ordained a bishop on 29 June 1973 in St. Peter's Basilica, Rome by Pope Paul VI.
Simon Agboso (Bursar), Sylvester Mawusi (Development officer) and Mr. Philip Odikro, (Cook) On 13 December 1984, Lodonu, then Bishop of Keta–Ho purchased and took over the management of Volta Commercial College, established in 1962 by Ofosu Appiah.
The Diocesan Secretariat was built in Ho and dedicated by Bishop Lodonu on 13 April 1985, in the presence of the Pro-Nuncio, Archbishop Ivan Dias.
The Centre dedicated to St. John Baptist Vianney, the Patron Saint of Parish Priests has accommodation, conference rooms and a restaurant.
In June 2004, the Bishop was appointed to negotiate peace between the Nkonyas and the Alavanyos as a Member and Vice Chairman of the Mediation Committee.
Through the efforts of the Catholic Diocesan Peace Building and Conflict Transformation Centre, the Mediation Committee received the necessary material and technical support enabling the communities of Nkonya and Alavanyo to reach a level of accommodation.