Francis Noble Ratcliffe OBE (11 January 1904 – 8 December 1970) was an Australian zoologist and conservationist.

After a short period working in London with the Empire Marketing Board, in 1929 he was brought to Australia by the CSIR to study flying foxes in northern New South Wales and Queensland, afterwards returning to Britain to work in the zoology department at the University of Aberdeen.

However, he returned to Australia permanently in 1935, working with the CSIR, and its successor the CSIRO, on such problems as wind erosion, termites and rabbit control.

He was also a founder of the Australian Conservation Foundation, serving as its first Honorary Secretary.

As well as various scientific papers and reports, books authored by Ratcliffe include: 1965 (with Frank Fenner) Myxmatosis, Cambridge University Press.