Francis James Zachariae (29 March 1852 – 6 September 1936) was a Danish businessman, local historic publisher and philanthropist.

He is today mainly remembered for publishing Før og Nu (I-IX and Supplements I-II) with topographical-historical images of Copenhagen from 1915 to 1927.

He graduated from Efterslægtselskabets Skole in 1868 and was thereafter an apprentice in S. Seidelin and Benny Goldschmidt in Copenhagen and Robinow & Majoribank in Glasgow.

His first wife was Adriane (Addy) Louise Beckett (1851-1910), a daughter of merchant on Saint Croix Francis B. and Ann Eliza Lang (1822–89).

In 1921, he founded the Nelly Zachariae Memorial Foundation, with circa DKK 1,300,000 in initial capital, supporting people who has experienced a deroute in life.