During the Siege of Hondarribia (1522-1524), he was listed in December 1523 along with his brother Pedro among the Navarrese loyalists not spared by the Emperor Charles V's pardon.
Eventually, following the general pardon decreed by the emperor Charles V that paved the ground to the end of the Siege of Hondarribia, he was appointed prior of Roncesvalles, later removed from Navarre.
[2] On May 4, 1556, Pope Paul IV appointed him Archbishop of Valencia and he was installed on Jun 22, 1556.
[2] While bishop, he was the principal co-consecrator of Tomás Garcia Martinez, Archbishop of Valencia (1544).
[2] He, along with his fellow Navarrese Martin Azpilcueta, defended Bartolome Carranza against the charges of Spanish Inquisition and the intent of King Philip II starting 1558.