Muller won the 2002 and 2003 Audie Award for Best Male Narrator for his readings of Clive Barker's Coldheart Canyon and Elmore Leonard's Tishomingo Blues, respectively.
On November 5, 2001, Muller was about to leave on a week-long motorcycle trip with a close relative when his wife Erika surprised him with the news that she was expecting their second child.
He sustained multiple fractures, lacerations, and abrasions, and was taken to Antelope Valley Hospital Medical Center in Lancaster, California, and went into cardiac arrest three times.
[5] In 2002, Stephen King, who had also experienced a life-threatening auto accident, organized a benefit for Muller with Pat Conroy, John Grisham, and Peter Straub.
In 2003, the Mullers moved to a house outside Raleigh, North Carolina, United States, that was modified specifically for Frank's therapeutic and rehabilitative needs.