During his period of medical studies and instruction, he was noted for his contributions to urology and lithotripsy.
He developed ideas on safer methods to remove bladder stones transurethrally, and his instruments served as models for subsequent devices.
He made multiple observations of the lunar surface that supported his beliefs, including his announcement of the discovery of a city in the rough terrain to the north of Schröter crater he named the Wallwerk.
This region contains a series of somewhat linear ridges that have a fishbone-like pattern, and, with the small refracting telescope he was using, could be perceived as resembling buildings complete with streets.
He is also noted for the discovery of bright caps on the cusps of the crescent Venus, which he attempted to explain by proposing that jungles on Venus grew more rapidly than in Brazil due to the proximity of the planet to the Sun, and that as a consequence the planet's inhabitants celebrated fire festivals during which they burned massive amounts of vegetation.