Frederick Augustus Muhlenberg (1818–1901) was an American educator and Lutheran clergyman who served as president of Muhlenberg College in Allentown, Pennsylvania, and as a Greek language and literature professor at the University of Pennsylvania in Philadelphia.

Muhlenberg was born to German Americans Frederick Augustus Hall Muhlenberg (1795–1867) and his wife Elizabeth Schaum in Lancaster, Pennsylvania, on August 25, 1818.

Muhlenberg was born at Lancaster, Pennsylvania, where his father was a physician and a trustee of Franklin College.

from the University of Pennsylvania where Benjamin Rush had been among his teachers.

[4] In 1876, Muhlenberg was appointed a professor of Greek at the University of Pennsylvania, where he remained until 1888.