Together with his brother, he accompanied the explorer Ludwig Leichhardt on his first expedition, on which Isaac proved himself an excellent bushman.
In 1847, Isaac and his men settled at a place called Dullacca (later the property of William Miles, Member of the Queensland Legislative Assembly), but he was very soon driven from that land by the aborigines.
[2] In 1854, he returned to England, where he married Caroline Sparkes, of St Johns, Bridgenorth, in Shropshire.
[2] Isaac was appointed to the Queensland Legislative Council on 25 August 1864 and served until his death on 12 July 1865.
[3] His widow remarried in 1866, to John Watts MLA, Queensland Secretary for Public Works, and returned with him to England in 1867.