Frederick William Mulkey (January 6, 1874 – May 5, 1924) was an American attorney and politician from the state of Oregon.

[1] He was raised there and attended the Portland Public Schools before enrolling in the University of Oregon in Eugene in 1892.

[2] In 1900, Mulkey joined the Portland City Council, serving until 1902, and was the president of the group in 1901.

[2] Mulkey was one of the first two senators to be elected under Oregon's direct primary law, in which senators were selected by popular vote, and then were officially elected to the position by the Oregon Legislative Assembly to comply with Article One of the U.S.

[2][4] On November 5, 1918, he was again elected to the U.S. Senate, this time to fill the unexpired term of Harry Lane, who had died on May 23, 1917.

[2] Mulkey replaced Charles L. McNary who had been appointed temporarily to the position, and who had won the election for a full-term in office starting in January 1919.