Rufus Cecil Holman (October 14, 1877 – November 27, 1959) was an American politician and businessman who served as a United States senator for a single term during World War II.

In 1937, he garnered publicity when he demonstrated the polluted state of the Willamette River by briefly holding a cage of salmon in the water, then quickly pulling them out dying to a shocked audience.

As Senator, Holman was critical of the foreign policy of President Franklin D. Roosevelt, taking a strongly isolationist position which placed him on the right wing of Oregon politics.

[6] As a Senator Holman was a staunch opponent of liberalizing immigration laws to allow easier immigration by Jews and other persecuted Europeans, a position which was deeply resented by Oregon's small but politically potent Jewish population, who quickly came to view the former KKK member Holman as antisemitic and who sought his electoral defeat.

It would be a good idea if the control of the international bankers over the common people of England was broken, and good if it was broken over the wages and savings of the common people of the United States.While attenuating his isolationism after the December 1941 attack on Pearl Harbor, coming to support the war effort, Holman's name remained indissolubly tied with the now politically unpopular isolationist position and he faced a high-profile challenge in the May 1944 Republican primary from progressive Wayne Morse.

[6] During his 1944 re-election bid, Holman publicly charged that Morse was a stalking horse for the Democrats, who, facing a severe deficit in party registrations in Oregon, needed a fissure in the Republican camp to capture the Senate seat in November.