The first meeting of the Fremantle Chamber of Commerce was held on 29 May 1873 at Maloney's Hotel,[2] with Mr. William Dalgety Moore serving as its first chairman (although the Chamber's own information disagrees with this, and suggests that it was William Marmion).

Nothing was done with the Chamber's landholdings until the block was exchanged for a site on Phillimore Street, adjacent to the Fremantle Fire Station,[3] which had become free when the railway yards moved to Midland.

[5] The current Chamber building was designed by Joseph Allen[6] and reflects the type of commercial structures erected in Fremantle during the expansive gold boom years.

It is a two-storey brick building with cement dressings on the front elevation.

The Chamber building was officially opened on 30 October 1912 by Sir Gerald Strickland (Governor of Western Australia).