Furcifer cephalolepis is used in the pet trade, with 8,583 specimens being exported from Grande Comore between 2004 and 2008.

Furcifer cephalolepis is native to Grande Comore (Ngazidja) in the Comoros Islands.

[3] Despite covering a small area and the fact that it has been used in the pet trade, the species is ranked as Least Concern (LC) because there are no signs that the population of the Furcifer cephalolepis are currently in decline.

[1] It is found in humid regions around the coast of Grande Comore and in forests in and around towns.

[4] Between 2004 and 2008, 8,583 living specimens of Furcifer cephalolepis were exported to be kept as pets from Grande Comore.