[3] Like its predecessor, Fuzion Frenzy 2 is a multiplayer game in which players choose colorful characters and compete to win a tournament made up of various mini-games.

Up to four players can play, with any positions not filled by humans occupied by computer-controlled opponents of configurable difficulty levels.

Discarding the orbs of Fuzion Frenzy, the new game instead directly awards players points after each mini-game based on their performance.

Additionally, players who finish first in mini-games are given a special item which increases their attack, defense, or health during the final stage on that particular planet.

At the conclusion of this final stage, the player with the highest cumulative point total wins the planet.

The single largest change in Fuzion Frenzy 2 as compared to the original is the inclusion of playable cards.

Their choice (i.e. which card to play, if any) is not revealed to other players, lending an element of strategy to the process.