Güntersleben is a municipality in the district of Würzburg in Bavaria in Germany.

In 1510 the village was hit by a severe fire, and in 1611 the plague claimed 141 victims.

As part of the Franconian Circle, Güntersleben was secularized in favor of Bavaria in 1803.

At the Peace of Pressburg of 1805, the area was confirmed to Ferdinand III, Grand Duke of Tuscany, as part of the Grand Duchy of Würzburg, and in 1814 with the defeat of Napoleon this became part of the Kingdom of Bavaria.

This Würzburg district location article is a stub.