GABA receptor agonist

GABA-α and GABA-ρ receptors produce sedative and hypnotic effects and have anti-convulsion properties.

Many commonly used sedative and anxiolytic drugs that affect the GABA receptor complex are not agonists.

Drugs that fall into this class exert their pharmacodynamic action by increasing the effects that an agonist has when potentiation is achieved.

Positive allosteric modulators work by increasing the frequency with which the chloride channel opens when an agonist binds to its own site on the GABA receptor.

GABA is the major inhibitory neurotransmitter in the brain, and GABA-like drugs are used to suppress spasms.