259114425ENSG00000115339ENSMUSG00000026994Q14435P70419NM_004482NM_015736NP_004473NP_056551Polypeptide N-acetylgalactosaminyltransferase 3 is an enzyme that in humans is encoded by the GALNT3 gene.

[5][6][7] This gene encodes UDP-GalNAc transferase 3, a member of the polypeptide GalNAc transferase (GalNAc-T) family.

This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis.

Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation is regulated by a repertoire of GalNAc-transferases.

The protein encoded by this gene is highly homologous to other family members; however, the enzymes have different substrate specificities.