Gene Ontology Term Enrichment

For example, the gene FasR is categorized as being a receptor, involved in apoptosis and located on the plasma membrane.

The output of the analysis is typically a ranked list of GO terms, each associated with a p-value.

The GO is actively used to classify genes from humans, model organisms and a variety of other species.

Certain types of high-throughput experiments (e.g., RNA seq) return sets of genes that are over- or under-expressed.

Functional profiling can be used to elucidate the underlying cellular mechanisms associated with the cancerous condition.