Son of Giuseppe dei Melzi Malingegni and Teresa dei Conti Prata, he was educated in the Collegio dei Nobili of Parma, where he met the Jesuit Juan Andrés, author of Dell'origine, progressi e stato attuale d'ogni letteratura.
[1] His career as a bibliophile began with the collection of incunabula and Greek and Latin classics, which were then dispersed and sold to libraries, such as the Biblioteca Nazionale Braidense, or to private individuals.
The part purchased by Frank Hall Standish, a wealthy English collector, including 3500 rare volumes and 250 incunabula, subsequently passed to Louis-Philippe of France, to his son Henri d'Orléans, Duke of Aumale, and after his death became part of the Condé Museum in Chantilly.
His library of over 30,000 volumes, inherited in the 1930s by the Meli-Lupi family of Soragna, was gradually dismembered.
[5] Gaetano Melzi was also a passionate music lover: he corresponded with many musicians of his time (including: Rossini, Donizetti, Bellini, Verdi), and left a voluminous correspondence, of considerable interest, currently kept at the Museo Teatrale alla Scala in Milan.