The shorts are by international filmmakers such as Antonio Padovan, Javier Chillon, Benni Diez, and Marinko Spahić, while Justin McConnell directed the wraparound.

One of the factions manages to infiltrate a compound on the other side with the aim of assassinating the president and liberating one of their own who has a natural immunity to the air and is the victim of torture and experiments.

A man named Dave tries to hide a dead body, but his smartphone's AI, Iris, has developed a sense of ethics and justice, challenging his actions and finding ways to thwart him.

[3] The feature is the brain-child of Little Terrors founder Justin McConnell, who wrote and directed the narrative links between the shorts, and Indiecan Entertainment's Avi Federgreen.

[24] A number of reviewers found similarities in the film or individual segments with the Black Mirror series,[3] usually as a point in the anthology's favour.

[27] Addison Wylie described the "claustrophobic wraparound short" by Justin McConnell as "semi-meta" and "pretty clever"; a bit of Mystery Science Theater 3000 dowsed in Heavy Metal: "The videos play for him – and for us – in a disjointed order; a forgivable trait since Galaxy of Horrors basically throws the audience into immediate abruptness.