Gambo is a town located in the Central African Republic prefecture of Mbomou.

The town is named after Gambo, a Nzakara chief who ruled the area in the years before 1931.

[3] In April 2015 Gambo was reported to be under control of Union for Peace in the Central African Republic.

[5] On 3 August 2017 heavy clashes erupted between Anti-balaka and UPC in the city resulting in 30 civilians and six volunteers from Red Cross killed and 150 houses being burnt.

[6] On 30 July 2018 Anti-balaka attacked UN convoy in Gambo injuring two Egyptian peacekeepers.