Located near Hiriya (now Ariel Sharon Park), it falls under the jurisdiction of Sdot Dan Regional Council.

[1] During the 18th and 19th centuries, the area of Ganot belonged to the Nahiyeh (sub-district) of Lod that encompassed the area of the present-day city of Modi'in-Maccabim-Re'ut in the south to the present-day city of El'ad in the north, and from the foothills in the east, through the Lod Valley to the outskirts of Jaffa in the west.

[2] The village was first established in 1950 by demobilised soldiers, but was later abandoned.

It was re-established in 1955 by Rassco (the Rural and Suburban Settlement Company) and took in residents from all over the country.

Its name is taken[3] from the Book of Amos 9:14; And I will turn the captivity of My people Israel, and they shall build the waste cities, and inhabit them; and they shall plant vineyards, and drink the wine thereof; they shall also make gardens, and eat the fruit of them.The Ganot interchange, a junction between Highway 1 and Highway 4, is located next to the moshav.