The line from Strasbourg to Lauterbourg was opened on 25 July 1876 by the Imperial Railways in Alsace-Lorraine (Kaiserliche Generaldirektion der Eisenbahnen in Elsaß-Lothringen).

[4] The Riviera-Express of the Compagnie des wagons-lits, connecting Berlin to Nice via Frankfurt, served the station from 3 December 1900.

It was abandoned when the First World War broke out[5] On 19 June 1919, the station became part of the network of the Administration des chemins de fer d'Alsace et de Lorraine (AL), as a result of the Allied victory in the First World War.

However, after the annexation of Alsace-Lorraine by Germany on 1 July 1940 during the Second World War, Deutsche Reichsbahn controlled the station and held it until the liberation of France (in 1944 –1945).

[9] Lauterbourg is a stop on the TER Alsace network, served by regional express trains on the Strasbourg-Ville–Lauterbourg route.