The Garfagnana (Italian: [ɡarfaɲˈɲaːna]) is a historical and geographical region of central Italy, today part of the province of Lucca, in Tuscany.

It is the upper valley or basin of the river Serchio, and thus lies between the main ridge of the Northern Apennines to the north-east and the Alpi Apuane to the west.

In the fifteenth century much of the territory came under the control of the d'Este family of Ferrara, and in 1847 the remaining part was absorbed into the Duchy of Modena.

[4] The spelt from the region, Farro della Garfagnana, has Indicazione Geografica Protetta status;[5] the area is also known for its lentils and for its porcini mushrooms.

The worst damage and largest number of deaths were at Villa Collemandina;[7] the greatest intensity was recorded there and at Fivizzano.