He played college football for the Ohio State Buckeyes and was selected 10th overall by the Jets in the 2022 NFL draft.

Wilson was born in Chicago on July 22, 2000, but grew up in Dublin, Ohio (a suburb of Columbus) until the age of 11.

[3] A five-star recruit, he was ranked as the second-highest receiver and committed to play college football at Ohio State University.

[4][5][6] As a true freshman at Ohio State in 2019, Wilson played in all 14 games and had 30 receptions for 432 yards and five touchdowns.

On November 21, 2020, Wilson became the second player in school history to record four straight games with at least 100 yards receiving.

[16] In Week 2, against the Cleveland Browns, he recorded his first two NFL touchdowns as part of an eight-reception, 102-yard performance in the 31–30 victory.