Knox was the youngest of four siblings, and although he was born in Ireland, he was raised in Scotland, to a family who all played a variety of musical instruments.

After studies at the Royal College of Music in London with Frederick Riddle, he became a member of Pierre Boulez's Ensemble InterContemporain in Paris (1983–1990) then joined the Arditti Quartet in London (1990–1997).

[3] In 2009 Garth Knox recorded another CD with ECM that was published in 2012: Saltarello – "a 14th-century fast Italian dance in ¾ time that survives today as a folk dance".

The compositions interpreted by the trio range from medieval music (Hildegard von Bingen, Guillaume de Machaut), renaissance (John Dowland), baroque (Henry Purcell, Antonio Vivaldi) to those of contemporaries like Kaija Saariaho and Garth Knox himself.

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