Gaspare Gori-Mancini (April 1653 – 16 July 1727) was an Italian prelate who was appointed as Bishop of Malta in 1722.

Gori-Mancini was born in the spring of 1653 in Rigomagno in the Province of Siena Italy.

[1] In 1723 Bishop Gori-Mancini, duly authorised by the Holy See, transferred the Seminary of the diocese from Mdina to Valletta.

Gori-Mancini was bishop during the reign of Grand Master António Manoel de Vilhena.

The tabernacle door and altar front with a medallion depicting the martyrdom of St. Catherine in the Chapel of Italy of the same Church were donated by him but later stolen by Napoleon.