Causation related to ulcers may involve severe pain which the patient may interpret as a heart condition or attack.

[1] Treatment of the condition depends upon the underlying cause; it can involve antibiotic treatment when Helicobacter pylori is related to an ulcer,[1] endoscopic therapies (such as dilation of the obstruction with balloons or the placement of self-expandable metallic stents), other medical therapies, or surgery to resolve the obstruction.

The main symptom is vomiting, which typically occurs after meals, of undigested food devoid of any bile.

Succussion splash is a splash-like sound heard over the stomach in the left upper quadrant of the abdomen on shaking the patient, with or without the stethoscope.

[citation needed] In most people with peptic ulcer disease, the oedema will usually settle with conservative management with nasogastric suction, replacement of fluids and electrolytes and proton pump inhibitors.