Gauri has done her post-graduation in organic chemistry at the University of Mumbai and maintains a chemistry-related blog.
[citation needed] Nigudkar started her career in 2004 with the national award-winning film Uttarayan.
She made her television debut in the 2007 series Betiyaan Apni Yaa Paraaya Dhan alongside Gautam Rode on Star Plus.
[4] She played the lead role of Krishna, the eldest daughter and central character of the show.
[5] Nigudkar has done several TV commercials including: Santoor Facewash, Whirlpool washing machine, Brooke Bond Taaza Tea,[6] California Almonds,[7] Mahindra Gio, Sony Pal, Tata I Shakti Dal, Waman Hari Pethe Jewellers, ICICI Home Loans, ICICI Prudential, Moov, Poppins, Senquel- F toothpaste, and Parle Must-Bites.