The series explores LGBTQ cultures around the world, as Page and Daniel meet different people during their travels and hear their stories.

Gaycation was introduced as part of the programming launch of Vice Media's new channel, Viceland.

[2] After Jonze recommended that Page be accompanied by a companion during the series, Page suggested Ian Daniel, a personal friend who was an art curator and the Director of Artistic Programs at The Civilians Theater Company, to be brought on as a co-host.

[8] A special episode aired on August 24, 2016, focusing on the aftermath of the mass shooting that occurred at the Pulse nightclub in Orlando, Florida.

[9][10] In January 2017, the series was nominated for a GLAAD Media Award for Outstanding Reality Program.