The game is set at an undetermined point in the future in which humanity is divided into two warring societies based on gender.

The Male faction are crass jocks obsessed with alcohol and other "manly" things while the Females are vapid Valley Girl archetypes preoccupied with fashion and other stereotypically feminine interests.

Regardless of the player's choice, the victorious faction will put the remaining members of the defeated sex into servitude.

GameSpot gave Gender Wars a "Fair" review score of 6.6/10, opining it is "a solid arcade strategy game that doesn't require lots of concentration, and has enough depth to keep things interesting.

"[2] A retrospective by Richard Cobbett of PC Gamer called it "a rubbish Syndicate wannabe," one which still handles its subject "better than Rex Nebular and the Cosmic Gender Bender.