Gene Howard Golub (February 29, 1932 – November 16, 2007), was an American numerical analyst who taught at Stanford University as Fletcher Jones Professor of Computer Science and held a courtesy appointment in electrical engineering.

His PhD dissertation was entitled "The Use of Chebyshev Matrix Polynomials in the Iterative Solution of Linear Equations Compared to the Method of Successive Overrelaxation" and his thesis adviser was Abraham Taub.

Gene Golub succumbed to acute myeloid leukemia on the morning of 16 November 2007 at the Stanford Hospital.

Gene Golub was an important figure in numerical analysis and pivotal to creating the NA-Net and the NA-Digest, as well as the International Congress on Industrial and Applied Mathematics.

In particular he published an algorithm together with William Kahan in 1970 that made the computation of the singular value decomposition (SVD) feasible and that is still used today.