Genkū-ji (源空寺), is a Buddhist temple located in the Higashiueno neighborhood of Taitō-ku, Tokyo, Japan.

The temple belongs to the Jōdo-shū sect of Japanese Buddhism and its honzon is a statue of Hōnen.

In 1604, Shogun Tokugawa Ieyasu made a grant of land to allow a proper temple to be established.

The temple was rebuilt, but was moved to its present location as part of the Tokugawa shogunate's urban remodeling plan for Edo.

The cemetery at Genku-ji contains the graves of a number of famous people: The temple is a two minute walk from Inaricho Station on the Tokyo Metro Ginza Line.