He was a friend and companion of Karl Marx and Friedrich Engels, who described Georg Weerth as the first and most significant poet of the German proletariat.
Georg Weerth wrote and edited the sketch page in the Neue Rheinische Zeitung, a German newspaper of which Karl Marx was editor-in-chief.
Like Engels, he devoted what time was left from his functions as a representative of a textile firm to studying the effects of the Industrial Revolution on the relationship between property owner and working class.
Weerth attended Chartist meetings and made friends with the leaders of the movement, such as George Julian Harney and Ernest Jones.
Shortly before his death, he wrote to Heinrich Heine that Cuba "would be the field where the great conflicts of the new world would be fought out first."