George Hamilton of Cairns (1635–1712) was a Church of Scotland minister who served as Moderator of the General Assembly in 1699.
In 1659 he was he ordained as a minister of the Church of Scotland, his first charge being Newburn in south Fife close to his birthplace.
In January 1699 he was elected Moderator of the General Assembly of the Church of Scotland, in place of Rev.
[4][5] He ceased preaching in January 1710 and appears to have stood unsuccessfully as a candidate as MP for Pittenweem against Sir John Anstruther.
Robert Clelland of Kilrenny (near Pittenweem) and Sophia Hamilton who married Thomas Spence, an Edinburgh lawyer.