George McGregor Harrison (July 19, 1895 – November 30, 1968) was an American leader of organized labor who built the Brotherhood of Railway & Steamship Clerks, Freight Handlers, Express & Station Employes into one of the "largest and best-governed".

Throughout his thirty-five years as Grand President (1928–1963), the Harrison administration and the Brotherhood remained above "suspicion and reproach".

[2] He served as an advisor to five American presidents and played a pivotal role in drafting the first Social Security measure that was enacted by Congress.

[4] With the drayage company mortgaged to provide security for the grocery store the Panic of 1907 led to the loss of both.

He was forced to find another job, this time as a page at the Planter's Hotel, where he remained through 1908 with his wages helping to support the rest of the family.

George M. Harrison was elected first local chairman of the grievance committee for the St. Louis lodge in what would become his first formal role.

When he assumed the role of Grand President, he brought an optimistic conviction that the Brotherhood could develop into a strong international union that inspired others.