During his time as a doctor for a mining company in Nenthead, he met his wife, Margaret Walton; however, she died after a year of marriage.
Shortly after his wife's death Savage accepted an appointment as an assistant medical officer at Bethlem Royal Hospital.
[2] At Bethlem and after he was sparing in his use of chemical sedation, although his freedom with physical restraint drew criticism from Henry Maudsley, J. C. Bucknill, and others.
Virginia Woolf saw him intermittently for a decade, and he is among the figures lampooned in the Sir William Bradshaw of Mrs.
His major public work was Insanity and Allied Neuroses, a reference book for students; published in 1884, it was revised and reissued in 1894 and 1907.