In 1887, Graham prosecuted Hannah Mary Tabbs and George H. Wilson for the murder and dismemberment of Wakefield Gains.

In his opening statement, he declared, "We will show by scientific testimony that Wakefield Gains was dismembered while there was yet life in the body.

Judge Hare accepted a plea of second degree murder and sentenced Wilson to twelve years in Eastern Penitentiary.

Graham worked closely with Detective Frank Geyer and requested he search for Pitezel's missing three children, whom Holmes took temporary custody of after Benjamin's death.

Geyer went on a cross-country, international search for the children, which led him to discover their remains in two locations, Irvington and Canada.