George Uppleby, of Bardney Hall, in Barton-upon-Humber, Lincolnshire and his wife Mary Fox.
He was educated at Shrewsbury School and admitted to Magdalene College, Cambridge on 16 December 1835.
In 1842 he rowed in the Cambridge Subscription Rooms eight which won the Grand Challenge Cup at Henley Royal Regatta.
Uppleby married firstly Emily Worsley, daughter of the Rev.
His daughter Laura Violet Uppleby married David George Hogarth.