He subsequently joined the faculty at the Johns Hopkins University Bloomberg School of Public Health and taught there for more than 50 years.

[3] In 1957, he led research in Bethel, Alaska, estimating the high burden of tuberculosis and demonstrating the drug isoniazid's effectiveness in preventing the disease.

He also may have conducted, the first case-cohort study reported in the literature, four decades ago, dealing with the relationships of maternal smoking to risks of neonatal and post-neonatal death.

During the past 30 years, a major part of my research has dealt with the relationships of serum or plasma concentrations of micronutrients, hormones, and viral antibodies to the subsequent development of cancer.

Another major portion of my research has been collaboration in studies of cardiovascular outcomes associated with serologic and clinical characteristics determined years earlier.

[6] George Comstock frequently quoted these words from Horace Mann's 1859 commencement speech at Antioch College:[7] I beseech you to treasure up in your hearts these my parting words: Be ashamed to die until you have won some victory for humanity.This struck him as the main purpose of living; as Comstock said, Most of us aren't going to win any big victories, but we can win little ones every day, and they mount up.