In Waleska, SR 108 crosses SR 140 and passes Reinhardt College, which is located at the intersection of the two routes, before continuing northeast through northern Cherokee County and into south-central Pickens County, paralleling I-575 to this point.

[1][2][3] Just inside Pickens County, the route makes a sudden turn to the southeast at its intersection with Henderson Mountain Road, nearly crosses back into Cherokee County, and then curves sharply to the north to run through the community of Cagle.

[1][2][3] The Georgia Department of Transportation average annual daily traffic (AADT) numbers for the year 2011 show a steady increase of the daily average vehicle load as SR 108 travel south to north.

Number decrease just slightly again in northern Cherokee County and southern Pickens County, with averages hovering around 2,700 vehicles, then jump sharply to stay around 5,000 vehicles both west and east of SR 5.

[8] This new stretch of roadway would eventually end up being removed from the state route system, and is named Refuge Road/South Main Street.

[9] It was then 1972 before this missing piece was integrated into the state route system, when this portion was designated as part of SR 156.

[17][6] By the end of 1946, the eastern half of this segment had a "sand clay, top soil, or stabilized earth" surface.