[2] Pickens County is part of the Atlanta-Sandy Springs-Roswell, Georgia metropolitan statistical area.

[4] During the Civil War, Company D of the 1st Georgia Infantry Battalion of the Union Army was raised in Pickens County.

Pickens County has seen very rapid growth with the building of Georgia State Route 515, locally referred to as the "four-lane".

[citation needed] Pickens County is home the Georgia Marble Festival.

The highest point in Pickens County is the 3,288-ft summit of Mount Oglethorpe, the southernmost peak in the Blue Ridge Mountains, and for a number of years, the southern terminus of the Appalachian Trail.