It connects the north-central part of Marion County with the Perry–Warner Robins area.

It heads north into Taylor County, and meets SR 90 in Mauk.

A few miles to the east, it briefly runs along the Macon–Houston county line.

A short distance later, SR 224 splits off to the southeast, while US 41/SR 7/SR 127 head northeast into the main part of the city on Courtney Hodges Boulevard and Commerce Street.

At Swift Street, SR 127 departs to the east, while US 41/SR 11 Business continues to the north-northeast SR 127 continues to the northeast, through urban areas of the county, until it meets its eastern terminus, an intersection with US 129/SR 247 in Kathleen.