She studied biology and joined the University of Utrecht where she became the first woman biologist to take up a position in Java in 1903.

She was involved in producing sereh-resistant hybrids[2] and clones and it was discovered that the disease did not infect cane above a certain altitude.

She took leave from 1912 to 1913 and returned to the experimental station in Cheribon where she worked on the isolation of a bacteria that cause leaf scald disease.

[3][4] She discovered a hot water treatment that helped remove sereh virus infection from setts prior to planting.

She served as a board member of the Willie Commelin Scholten Phytopathology Laboratory until 1956.