German submarine U-217 was a Type VIID mine-laying U-boat of Nazi Germany's Kriegsmarine during World War II.

The submarine was powered by two Germaniawerft F46 supercharged four-stroke, six-cylinder diesel engines producing a total of 2,800 to 3,200 metric horsepower (2,060 to 2,350 kW; 2,760 to 3,160 shp) for use while surfaced, two AEG GU 460/8-276 double-acting electric motors producing a total of 750 shaft horsepower (760 PS; 560 kW) for use while submerged.

U-217 was fitted with five 53.3 cm (21 in) torpedo tubes (four fitted at the bow and one at the stern), twelve torpedoes, one 8.8 cm (3.46 in) SK C/35 naval gun, 220 rounds, and an anti-aircraft gun, in addition to five mine tubes with fifteen SMA mines.

U-217 completed three patrols and sank three ships totalling 10,651 gross register tons (GRT).

She was sunk on 5 June 1943 in the mid-Atlantic with all hands by depth charges dropped by Grumman TBF Avengers from the escort carrier Bogue (CVE-9).