Gerolamo Gradenigo (Latin: Hieronymus Gradonicus 1597 – 1657) was Patriarch of Aquileia from 1656 to 1657.

He received the episcopal consecration in the monastic church of Santa Maria degli Angeli, Murano on 21 September 1646 by the hands of the bishop of Torcello Marco Antonio Martinengo.

At the death of his brother Marco, on 16 February 1656, Gerolamo became immediately Patriarch of Aquileia.

Already on 16 March 1656 the new patriarch asked the pope to appoint his relative Giovanni Delfino as coadjutor bishop of Aquileia, a request which was accepted on 23 June.

[1] Gerolamo Gradenigo died on 19 December 1657, and was buried in the church of San Clemente in Venice.