In 1131, wealthy merchant Pietro Gattilesso funded the construction of a church and a hospice for pilgrims and soldiers heading to the Holy Land on an island located in the Venetian Lagoon.
In 1643, to fulfil a vow made during the plague epidemic that struck the city in 1630, Venetians funded the building of a new chapel, modelled on the Holy House of Loreto, inside the church, where the main altar was.
They entrusted Andrea Cominelli, who perpetuated the family's coat of arms above the entrance and added reliefs of scenes from battles commemorating the Morosini's victories in the war against the Turks.
The church was restored in 2003 as part of the project that made the adjacent buildings into a luxury hotel, which is now managed by Kempinski Group.
[2] Between 2013 and 2014 Permak group - the current owner of San Clemente Island[3] - launched further renovations while retaining the historic character.