The Gesuati Altarpiece is a 1444 tempera and gold on poplar panel altarpiece by Sano di Pietro, produced for San Girolamo, a Jesuati monastery in Siena.
[2] The main panel shows the Madonna and Child enthroned flanked by six angels, with Blessed Giovanni Colombini (founder of the Jesuati order) kneeling in prayer before them.
Down the outer left-hand edge are three panels showing (from bottom to top) saints Peter, Anthony Abbot and Mary Magdalene, with an equivalent set down the right-hand edge James the Great, Ephrem the Syrian and Catherine of Alexandria.
[3] The central top register shows Christ the Redeemer enthroned and blessing, flanked by double pairs of seraphim with coloured wings.
Either side are four more panels showing an Annunciation and Saints Cosmas and Damian.