George was born in the city of Koprulu, Rumelia Ottoman Empire, in 1600 ( Today part of the Republic of North Macedonia ).
While in Istanbul, he became close friends with the Grand Vizier Köprülü Mehmed Pasha and helped him on to high positions.
[1] From him are descended the numerous branches of the family which became notable in the history of Moldavia and Wallachia.
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